Polar Overdominance at the Ovine callipyge Locus
- 12 July 1996
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 273 (5272), 236-238
- https://doi.org/10.1126/science.273.5272.236
Abstract
An inheritable muscular hypertrophy was recently described in sheep and shown to be determined by the callipyge gene mapped to ovine chromosome 18. Here, the callipyge phenotype was found to be characterized by a nonmendelian inheritance pattern, referred to as polar overdominance, where only heterozygous individuals having inherited the callipyge mutation from their sire express the phenotype. The possible role of parental imprinting in the determinism of polar overdominance is envisaged.Keywords
This publication has 11 references indexed in Scilit:
- Mapping quantitative trait loci controlling milk production in dairy cattle by exploiting progeny testing.Genetics, 1995
- Parental imprinting of autosomal mammalian genesCurrent Opinion in Genetics & Development, 1994
- Chromosomal localization of the callipyge gene in sheep (Ovis aries) using bovine DNA markers.Proceedings of the National Academy of Sciences, 1994
- The polar-lethal Ovum mutant gene maps to the distal portion of mouse chromosome 11.Genetics, 1992
- Genetic analysis of genomic imprinting: An Imprintor-1 gene controls inactivation of the paternal copy of the mouse Tme locusCell, 1992
- The locus Om, responsible for the DDK syndrome, maps close to Sigje on mouse Chromosome 11Mammalian Genome, 1992
- Maternal uniparental disomy for chromosome 14.Journal of Medical Genetics, 1991
- Trans-sensing effects from Drosophila to humansCell, 1991
- Epigenetic control of transgene expression and imprinting by genotype-specific modifiersCell, 1990
- A GENETICALLY DETERMINED INCOMPATIBILITY SYSTEM BETWEEN SPERMATOZOA AND EGGS LEADING TO EMBRYONIC DEATH IN MICEReproduction, 1974