A gradient of sex linkage in the pseudoautosomal region of the human sex chromosomes
- 1 January 1986
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 319 (6051), 291-295
- https://doi.org/10.1038/319291a0
Abstract
Three independent pseudoautosomal loci are linked to sex determination at frequencies which define a gradient of linkage. The segregation patterns of these loci indicate that X/Y recombination results from a single obligatory meiotic crossing-over in the pseudoautosomal region. Recombination in male germ cells in the terminal regions of the short arms of the X and Y chromosomes is 10-fold greater than between the same regions of the X-chromosomes in female germ cells.Keywords
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