Accumulation of Mad2–Cdc20 complex during spindle checkpoint activation requires binding of open and closed conformers of Mad2 in Saccharomyces cerevisiae
Open Access
- 3 July 2006
- journal article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 174 (1), 39-51
- https://doi.org/10.1083/jcb.200602109
Abstract
The spindle assembly checkpoint (SAC) coordinates mitotic progression with sister chromatid alignment. In mitosis, the checkpoint machinery accumulates at kinetKeywords
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