Fluorameisensäure-1-adamantylester, ein neues Reagenz zur Einführung der 1-Adamantyloxycarbonyl-Schutzgruppe
- 1 January 1976
- journal article
- research article
- Published by Walter de Gruyter GmbH in Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie
- Vol. 357 (2), 1647-1650
- https://doi.org/10.1515/bchm2.1976.357.2.1647
Abstract
1-Adamantyl fluoroformate was prepared from 1-adamantol and fluorophosgene. The crystalline and stable fluoroformate was allowed to react with amino acids to give the corresponding 1-adamantyloxycarbonyl derivatives in consistently high yields. This new reagent was ideally reactive for acylation of the imidazole function of histidine and histidyl-peptides.This publication has 1 reference indexed in Scilit:
- Adamantyloxycarbonyl, a New Blocking Group. Preparation of 1-Adamantyl Chloroformate1Journal of the American Chemical Society, 1966