Colonic Villous Adenoma
- 12 February 1982
- journal article
- research article
- Published by American Medical Association (AMA)
- Vol. 247 (6), 829-830
- https://doi.org/10.1001/jama.1982.03320310077042
Abstract
A colonic villous adenoma removed from a glucose-6-phosphate dehydrogenase (G6PD) heterozygous patient was studied. The mucosal cells were separated to eliminate the contaminating nonadenoma cells by enzymatic disaggregation followed by isokinetic gradient centrifugation. The mucosal cells from this colonic polyp contained a single G6PD isoenzyme. Our study demonstrates clonality of this type of polyp and the value of the cell separation techniques in the experimental oncology. (JAMA1982;247:829-830)Keywords
This publication has 3 references indexed in Scilit:
- The Origin and Development of Human Tumors Studied with Cell MarkersNew England Journal of Medicine, 1974
- Value of Genetic Variants of Glucose-6-Phosphate Dehydrogenase in Tracing the Origin of Malignant TumorsNew England Journal of Medicine, 1967
- THE NORMAL HUMAN FEMALE AS A MOSAIC OF X-CHROMOSOME ACTIVITY: STUDIES USING THE GENE FOR G-6-PD-DEFICIENCY AS A MARKERProceedings of the National Academy of Sciences, 1962