CHANGES IN CERTAIN BLOOD CONSTITUENTS PRODUCED BY PARTIAL INANITION AND MUSCULAR FATIGUE

Abstract

Young dogs were fatigued by running on a horizontal treadmill and by swimming in water at 38[degree] C. Blood samples for analysis of serum pH, total CO2, lactate, phosphate, K and sugar were drawn before and after exercise and twice during recovery. Periods on normal diet alternated with periods of undernutrition. Swimming produced a marked decrease in bicarbonate and increase in lactate, displacement of acid-base balance in the direction of fixed acid excess; treadmill exercise, a smaller change in bicarbonate and lactate, displacement of acid-base balance towards CO2 deficit. Exercise accompanied by undernutrition produced changes in the same direction as in the normal animal but of greater magnitude; return to the normal was slow.