Neutral-Lipid Analysis Reveals Elevation of Acylglycerols and Lack of Cholesterol Esters in Plasmodium falciparum -Infected Erythrocytes
Open Access
- 1 October 2003
- journal article
- Published by American Society for Microbiology in Eukaryotic Cell
- Vol. 2 (5), 1128-1131
- https://doi.org/10.1128/ec.2.5.1128-1131.2003
Abstract
Here we show that blood-stage Plasmodium falciparum organisms accumulate a high mass of triacylglycerol and diacylglycerol. However, we failed to detect cholesterol esters, a second neutral lipid species reported to be important for a related apicomplexan, Toxoplasma gondii . Evidence for P. falciparum and T. gondii homologues of acyl coenzyme A:diacylglycerol acyltransferase suggests that acylglycerols may be the conserved neutral lipids in apicomplexans.Keywords
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