Effect of Anoxia on Protein Metabolism in Subcellular Fractions of Rabbit Brain
- 1 March 1974
- journal article
- research article
- Published by Wolters Kluwer Health in Stroke
- Vol. 5 (2), 226-229
- https://doi.org/10.1161/01.str.5.2.226
Abstract
The effect of cerebral anoxia on leucine incorporation into proteins of various subcellular fractions from rabbit brain was studied by using a previously reported in vitro model. Although the decrease in leucine incorporation was observed earlier in nuclei and microsomes, other fractions also demonstrated a rapid decrease. These results were quite different from the pattern of leucine incorporation observed in a type of reversible suppression produced with diphenylhydantoin.Keywords
This publication has 4 references indexed in Scilit:
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- SUBCELLULAR DISTRIBUTION OF RADIOACTIVITY IN NEURONAL AND GLIAL‐ENRICHED FRACTIONS AFTER INCORPORATION OF [3H]LEUCINE IN VIVO AND IN VITROJournal of Neurochemistry, 1971
- Effect of diphenylhydantoin on protein metabolism in the central nervous system: Study of subcellular fractionsExperimental Neurology, 1971
- Effect of hypoxia on protein metabolism in neuron- and neuroglia cell-enriched fractions from rabbit brainExperimental Neurology, 1970