FURTHER STUDIES OF THE METABOLISM OF OESTRADIOL IN MAN
- 1 May 1961
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 37 (1), 57-62
- https://doi.org/10.1530/acta.0.0370057
Abstract
Oestradiol-17[beta] labeled with tritium in the a orientation of C-17 was administered intravenously to two women. Oestrone, oestradiol, oestriol and 3[alpha]-hydroxypregnan-20-one were isolated from the urine and the isotope incorporated into these metabolites was measured. The results supported the prior conclusion that oestradiol is rapidly oxidized in vivo and that oestrone serves as the immediate precursor of oestriol. A possible explanation is offered for the presence of trace quantities of isotope in oestriol and 3[alpha]-hydroxypregnan-20 one.Keywords
This publication has 4 references indexed in Scilit:
- Oxidative Metabolism of EstradiolJournal of Biological Chemistry, 1960
- Determination of Carbon-14 and Tritium in Blood and Other Whole Tissues. Liquid Scintillation Counting of TissuesAnalytical Chemistry, 1960
- A Comparison of Methods for the Analysis of Estrone, Estradiol, and Estriol in Extracts of Human UrineJournal of Biological Chemistry, 1958
- THE TRANSFORMATION OF CHOLESTEROL TO COPROSTANOLJournal of Biological Chemistry, 1954