Stille Cross-Couplings of Unactivated Secondary Alkyl Halides Using Monoorganotin Reagents
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- 23 December 2004
- journal article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 127 (2), 510-511
- https://doi.org/10.1021/ja0436300
Abstract
The first catalyst that achieves Stille cross-couplings of secondary (as well as primary) alkyl halides has been developed. The method employs easily handled and inexpensive catalyst components (NiCl2 and 2,2‘-bipyridine) and, through the use of monoorganotin reagents, avoids the formation of toxic and difficult-to-remove triorganotin side products.Keywords
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