Effect of Liposomal and Free Bisphosphonates on the IL-1β, IL-6 and TNFα Secretion from RAW 264 Cells in Vitro
- 1 January 1995
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 12 (6), 916-922
- https://doi.org/10.1023/a:1016281608773
Abstract
Purpose. In order to evaluate the possible antiinflammatory action of bisphosphonates, the effect of the drugs on the secretion of proinflammatory cytokines (IL-lβ, IL-6 and TNFα) from macrophages...Keywords
This publication has 24 references indexed in Scilit:
- Clodronate (dichloromethylene bisphosphonate) inhibits LPS-stimulated IL-6 and TNF production by raw 264 cellsLife Sciences, 1994
- Anti-inflammatory actions of steroids: molecular mechanismsTrends in Pharmacological Sciences, 1993
- The effects of liposome-encapsulated and free clodronate on the growth of macrophage-like cellsin vitro: The role of calcium and ironCalcified Tissue International, 1993
- Interleukin-6 and its relation to inflammation and diseaseClinical Immunology and Immunopathology, 1992
- BisphosphonatesDrugs, 1991
- Augmentation and Suppression of Release of Tumor Necrosis Factor from Macrophages by Negatively Charged PhospholipidsJapanese Journal of Cancer Research, 1991
- Cytokine Assays: Role in Evaluation of the Pathogenesis of AutoimmunityImmunological Reviews, 1991
- Bisphosphonates in vitro specifically inhibit, among the hematopoietic series, the development of the mouse mononuclear phagocyte lineageJournal of Bone and Mineral Research, 1990
- Comparison of the Distribution of Three Bisphosphonates in MiceBasic & Clinical Pharmacology & Toxicology, 1990
- Effect of bisphosphonates on production of interleukin 1-like activity by macrophages and its effect on rabbit chondrocytesBone, 1985