Effect of Methionine Supplements on Hepatic Injury Produced by Carbon Tetrachloride

Abstract

Supplements of methionine decreased the degree of liver damage produced by toxic agents (CC14) in protein-depleted adult dogs. In dogs with a normal protein intake of 20% or 41% casein, methionine supplements did not decrease the degree of hepatic damage produced by CC14 as judged by serum phosphatase values (Bodansky method) or bromsulphalein retention (method of Rosenthal and White).