Inhibitory Effect of (—)‐Epigallocatechin Gallate on Carcinogenesis with N‐Ethyl‐N′‐nitro‐N‐nitrosoguanidine in Mouse Duodenum
- 1 June 1989
- journal article
- research article
- Published by Wiley in Japanese Journal of Cancer Research
- Vol. 80 (6), 503-505
- https://doi.org/10.1111/j.1349-7006.1989.tb01666.x
Abstract
(-)-Epigallocatechin gallate (EGCG) is the main polyphenolic constituent of green tea infusion and inhibits tumor promotion by teleocidin in two-stage carcinogenesis on mouse skin. In this work, EGCG was found to inhibit tumor promotion in the gastrointestional tracts in a model system of mouse duodenal carcinogenesis with N-ethyl-N''-nitro-N-nitrosoguanidine. The duodenal tumors that developed were studied stereomicroscopically and histologically.Keywords
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