Relationship between ketogenesis and gluconeogenesis in isolated hepatocytes from newborn rats
- 15 November 1981
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 200 (2), 429-433
- https://doi.org/10.1042/bj2000429
Abstract
In hepatocytes from 1-day-old rats, active gluconeogenesis occurs in parallel with active ketogenesis, although the carbon atoms of non-esterified fatty acids do not participate in glucose synthesis. Once a significant ketogenesis is established, a further increase does not enhance gluconeogenesis. Indeed, octanoate is more ketogenic than oleate, but stimulates gluconeogenesis to a similar extent.This publication has 24 references indexed in Scilit:
- The effects of inhibition of gluconeogenesis in suckling newborn ratsBiochemical Journal, 1977
- Active transport of butyrobetaine and carnitine into isolated liver cellsBiochimica et Biophysica Acta (BBA) - Biomembranes, 1976
- Fuels, Hormones, and Liver Metabolism at Term and during the Early Postnatal Period in the RatJCI Insight, 1973
- CYTOMORPHOMETRY OF DEVELOPING RAT LIVER AND ITS APPLICATION TO ENZYMIC DIFFERENTIATIONThe Journal of cell biology, 1972
- Control factors affecting gluconeogenesis in perfused rat liver. Effects of 4-pentenoic acid.1970
- HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLSThe Journal of cell biology, 1969
- Control mechanisms of gluconeogenesis and ketogenesis. I. Effects of oleate on gluconeogenesis in perfused rat liver.1969
- Role of Free Fatty Acids in Glucose HomeostasisArchives of Internal Medicine, 1969
- Gluconeogenesis in the perfused rat liverBiochemical Journal, 1966
- Enzymic determination of d(−)-β-hydroxybutyric acid and acetoacetic acid in bloodBiochemical Journal, 1962