Studies on Effect of Gonadectomy on Dental Caries Activity in White Rats and in Cotton Rats

Abstract

In caries-susceptible white rats and cotton rats fed a highly purified caries-producing diet, there was a consistent tendency toward a lesser avg. incidence of tooth decay in the gonadectomized rodents than in the intact littermates. The reduction in dental caries incidence was appreciably higher among orchidectomized males than among ovariectomized females. No difference was observed between the avg. dental caries activity in males and females for each species.