Effects of RES "blockade" on antibody formation. II. Cytokinetics of the secondary haemolysin response and suppressed immunological "memory" in mice treated with carbon particles.
- 1 October 1969
- journal article
- Vol. 17 (4), 535-50
Abstract
Suppression of the primary immune response by treatment of mice with carbon 1 day before initial immunization markedly interfered with development of immunological `memory', since such mice responded to a subsequent challenge injection of RBCs by formation of mainly IgM PFCs and serum antibody. Appearance of IgG PFCs and 2-ME resistant antibody was delayed several days in these carbon treated animals, indicating failure of a typical secondary response. The immune response of these animals was similar to that of a primary response of control animals to a single injection of red cells.This publication has 26 references indexed in Scilit:
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