Fast Analysis of Tissue Catechols Using a Short, High-Efficiency (3 μm) LC Column and Amperometric Detection
- 1 May 1984
- journal article
- research article
- Published by Taylor & Francis in Journal of Liquid Chromatography
- Vol. 7 (6), 1211-1220
- https://doi.org/10.1080/01483918408074038
Abstract
Tissue catecholamines were analyzed in less than 8 minutes per sample, using a 5 cm LC column, packed with a 3 μm particle size reverse phase sorbent, under conditions which permit fast analysis of tissue extracts of up to 70 μl with no loss in resolution or theoretical plate height. The sensitivity of amperometric detection makes this method suitable for analyzing small amounts of catechols in tissues such as rat brain prefrontal cortex.Keywords
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