The Curative Effect of a High-Calcium Diet on Senile Osteoporosis

Abstract

Long-term calcium-deficient diets produced osteoporosis in rats, which was characterized by chemical, roentgenographic and microradiographic studies. A normally mineralized skeleton could be restored by feeding a dietary supplement of simulated nonprotein milk solids containing calcium phosphate. These observations suggest that osteoporosis in humans may result from long-term negative calcium balance and that calcium phosphate supplements in the diet may be used to cure the condition.