The immunizing potency of alcohol-killed and alcohol-preserved typhoid vaccine after storage for ten Years
- 1 June 1951
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 49 (2-3), 288-298
- https://doi.org/10.1017/s0022172400044168
Abstract
1. Alcohol-killed and alcohol-preserved typhoid vaccine retains its power of stimulating Vi- and O-antibody formation unimpaired during storage at 1–2° C. for at least 10 years.2. The Vi antibody induced by immunization with the 10-year-old vaccine possesses full ‘functional efficacy’ in passive-immunity tests in mice.3. The expiry date of this type of vaccine can be extended to a period of 10 years, provided the vaccine is kept in cold storage.4. Alcoholized vaccine can serve as ‘standard vaccine’ in any future attempt at standardization of the potency of typhoid vaccine.Keywords
This publication has 13 references indexed in Scilit:
- Bacteriophage, virulence and agglutination tests with a strain of Salmonella typhi of low virulenceEpidemiology and Infection, 1951
- The preparation, testing and standardization of typhoid vaccineEpidemiology and Infection, 1951
- An outbreak of typhoid fever in the Middle EastEpidemiology and Infection, 1948
- TYPING OF TYPHOID BACILLI WITH Vi BACTERIOPHAGEThe Lancet, 1947
- The preservation of Vi antigen in T.A.B.C. vaccine: With a note on combined active immunization with T.A.B.C. vaccine in tetanus formol-toxoidEpidemiology and Infection, 1942
- Antibody Response and Systemic Reactions after Inoculation of a New Type of T.A.B.C. VaccineBMJ, 1941
- A New Type of Typhoid and Paratyphoid VaccineBMJ, 1941
- The titration of therapeutic anti-typhoid serumEpidemiology and Infection, 1938
- The preparation of anti-typhoid serum in the horse for therapeutic use in manEpidemiology and Infection, 1938
- Potency of Typhoid and Paratyphoid Vaccines When Freshly Prepared and After StorageThe Journal of Infectious Diseases, 1937