The effect of cyclic AMP on the rabbit corneal endothelial fluid pump
- 1 January 1982
- journal article
- research article
- Published by Taylor & Francis in Current Eye Research
- Vol. 2 (8), 565-567
- https://doi.org/10.3109/02713688209069182
Abstract
Perfusing presvollen deepithelialized rabbit cornea in vitro on its endothelial side with balanced salt solution containing physiological glucose concentration and 10–6M adenosine, we can obtain “temperature reversal” from 500–520p to less than 400µ, during 7 hours. Low concentrations of adenosine improve the fluid pump supposedly by inhibiting adenylate cyclase, since c-AMP inhibits the pump.Keywords
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