A signal sequence is not sufficient to lead β-galactosidase out of the cytoplasm
- 1 July 1980
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 286 (5771), 356-359
- https://doi.org/10.1038/286356a0
Abstract
Escherichia coli strains were constructed in which lacZ, the gene for the cytoplasmic enzyme .beta.-galactosidase, is fused to lamB, the gene for an outer membrane protein. One such strain produces a .beta.-galactosidase which remains cytoplasmic even though it possesses the complete signal sequence of the lamB protein precursor at the amino-terminal end.This publication has 52 references indexed in Scilit:
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