Abstract
SUMMARY: 1. The chemical properties of a gonadotrophic substance, gonadotrophin A (GA), prepared from human urine, have been studied. 2. Preparations of GA from various sources showed marked differences in biological activity, but not in chemical properties. Highly active preparations, however, showed greater u.v. absorption between the wavelengths of 280 and 295 mμ. 3. Methods are described for the purification of GA by countercurrent distribution and partition chromatography.