Evanston Dental Caries Study 22. A Study of Fluoride Deposition in Bone

Abstract

Fluoride deposition in the iliac crest increases with the increment of age and time of exposure. The variations in this function can be attributed to the dietary habits of the subjects and to the effects of renal malfunctions on the level of fluoride accumulation in bone. It seems likely that the fluoride deposition in bone proceeds fairly rapidly during the first 5-9 years of fluoridation. This accumulation of fluoride occurs at a much slower rate in the following years. There is a rapid increase in the level of fluoride concentration in bone up to the age of 60-69, after which there is a tendency for fluoride accumulation to level off or proceed at a much slower rate.