The relationship between flow and electrolyte secretion in the canine pancreas
Open Access
- 1 August 1970
- Vol. 11 (8), 700-708
- https://doi.org/10.1136/gut.11.8.700
Abstract
The response of the pancreatic bicarbonate secretory mechanism to secretin and the relationship between bicarbonate concentration and flow rate in pancreatic juice have been re-examined following reports describing decreasing levels of bicarbonate concentration at high flow rates. Both anaesthetized and chronic fistula dogs were used. The results show that when high doses of secretin elicit high rates of flow of pancreatic juice the bicarbonate concentration rises to a peak which is constant over a wide range of stimulation and flow rates.Keywords
This publication has 13 references indexed in Scilit:
- RESPONSE TO SECRETIN IN MAN1968
- Relationship between Bicarbonate, Chloride, and Volume Flow at High Secretory Rates in the Pancreatic Juice of the DogScandinavian Journal of Gastroenterology, 1968
- [Study of the exocrine function of the human pancreas, using continuous perfusions of secretin. I. Influence of increasing doses on secretion of water and electrolytes].1967
- Relation between bicarbonate concentration and rate of canine pancreatic secretionAmerican Journal of Physiology-Legacy Content, 1965
- Effects of acid-base changes and carbonic anhydrase inhibition on pancreatic secretionAmerican Journal of Physiology-Legacy Content, 1963
- Maximum alkaline (bicarbonate) output of the dog pancreasAmerican Journal of Physiology-Legacy Content, 1963
- The Duodenal Secretion in Man as a Function of Secretin Dose and Secretin InactivationGastroenterology, 1962
- Action of secretin on pancreatic secretionAmerican Journal of Physiology-Legacy Content, 1961
- The Composition of Pancreatic Juice as Compared to Sweat, Parotid Saliva and Tears.Acta Physiologica Scandinavica, 1956
- The mechanism of the functional hyperaemia in the submandibular salivary glandThe Journal of Physiology, 1955