A common mechanism of transcriptional activation by the three positive regulators, VirG, PhoB, and OmpR
- 9 April 1990
- journal article
- review article
- Published by Wiley in FEBS Letters
- Vol. 263 (1), 1-4
- https://doi.org/10.1016/0014-5793(90)80691-b
Abstract
VirG, PhoB, and OmpR are positive regulators of the virulence, phosphate, and osmolarity regulons, respectively. Their target genes are attended with one or more significant blocks of similar 6-bp sequences in their regulatory regions. The distance between the block(s) and transcriptional start site varies with the target genes, but the blocks are located in a similar manner phase-specific to the promoter sequences. On the basis of these facts, we offer a novel model of transcriptional activation common to these regulators.Keywords
This publication has 16 references indexed in Scilit:
- Signal transduction in the phosphate regulon of Escherichia coli involves phosphotransfer between PhoR and PhoB proteinsJournal of Molecular Biology, 1989
- Putative start codon TTG for the regulatory protein VirG of the hairy-root-inducing plasmid pRiA4Gene, 1989
- Signal structure for transcriptional activation in the upstream regions of virulence genes on the hairy-root-inducing plasmid A4Nucleic Acids Research, 1988
- Regulation of the phosphate regulon of Escherichia coliJournal of Molecular Biology, 1988
- Stereospecific positioning of the cis-acting sequence with respect to the canonical promoter is required for activation of the ompC gene by a positive regulator, ompR, in Escherichia coliJournal of Molecular Biology, 1988
- Conserved domains in bacterial regulatory proteins that respond to environmental stimuliCell, 1987
- The Role of Virulence Regulatory Loci in Determining Agrobacterium Host RangePublished by Springer Nature ,1987
- Nucleotide sequence of the phoB gene, the positive regulatory gene for the phosphate regulon of Escherichia coli K-12Journal of Molecular Biology, 1986
- Molecular analysis of mutant ompR genes exhibiting different phenotypes as to osmoregulation of the ompF and ompC genes of Escherichia coliMolecular Genetics and Genomics, 1986
- E. coli RNA polymerase interacts homologously with two different promotersCell, 1980