Inhibition of Calcium Oxalate Crystal Growth in Urine during Treatment with Allopurinol
- 1 June 1980
- journal article
- research article
- Published by Wiley in British Journal of Urology
- Vol. 52 (3), 189-192
- https://doi.org/10.1111/j.1464-410x.1980.tb02957.x
Abstract
Twelve male patients with urolithiasis were treated with 300 mg allopurinol daily. Urinary urate decreased from 251 .+-. 55 to 156 .+-. 19 (mean .+-. SD) mmol per mol creatinine. The inhibition of calcium oxalate crystal growth was measured in an in vitro system and the inhibition index increased from 0.51 .+-. 0.06 to 0.57 .+-. 0.08 (mean .+-. SD). Urinary citrate excretion was unaffected by the treatment.This publication has 10 references indexed in Scilit:
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