Gonadotropin Binding and Aromatase Activity in Granulosa Cells of Young Proestrous and Old Constant Estrous Rats1
- 1 March 1979
- journal article
- research article
- Published by Oxford University Press (OUP) in Biology of Reproduction
- Vol. 20 (2), 182-190
- https://doi.org/10.1095/biolreprod20.2.182
Abstract
This study was designed to determine whether chronic anovulation in old constant estrous rats is associated with alternations in gonadotropin binding and/or aromatase enzyme activity of granulosa cells. Granulosa cells, isolated from mature Graafian follicles of old constant estrous rats (25-26 months of age) and young proestrous rats (4-5 months of age), were tested for their capacity of 1) bind human [1 2 5I] iodo-chorionic gonadotropin specifically and to 2) aromatize androstenedione into estrogens.This publication has 11 references indexed in Scilit:
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