Hanrahan and Miller1have recently called attention to an association of chronic arthritis, splenomegaly and leukopenia, first reported by Felty2in 1924. In the voluminous literature dealing with chronic arthritis, splenomegaly and leukopenia as separate entities, the simultaneous occurrence of the three abnormalities is not mentioned except in these two papers. There was marked improvement following splenectomy in both the arthritic and the leukopenic features of the case reported by Hanrahan and Miller.1The present report is offered with additional observations on a similar case and with a description of the apparently transient effect of splenectomy. REPORT OF CASE L. S., a white woman, aged 40, admitted to the medical service, Sept. 20, 1932, complained of pain in the joints of four years' duration. Except for a brother who suffers from arthritis, the details of which are unknown, the family history was irrelevant. There was nothing in the