Inhibition of visceral pain by electrical stimulation of the periaqueductal gray matter
- 1 March 1976
- journal article
- research article
- Published by Wolters Kluwer Health in Pain
- Vol. 2 (1), 43-48
- https://doi.org/10.1016/0304-3959(76)90045-2
Abstract
Electrical stimulation of the periaqueductal gray matter (PGM) can result in powerful analgesia to pain of somatic origin. A visceral pain test was developed employing i.p. injection of hypertonic saline which yielded a writhing response in the adult rat more reliably than other pain-producing substances. With this test writhing and the response to radiant heat (tail flick test) were completely inhibited in all animals with PGM electrode placements.This publication has 20 references indexed in Scilit:
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