Simvastatin Reduces Expression of Cytokines Interleukin-6, Interleukin-8, and Monocyte Chemoattractant Protein-1 in Circulating Monocytes From Hypercholesterolemic Patients
- 1 July 2002
- journal article
- research article
- Published by Wolters Kluwer Health in Arteriosclerosis, Thrombosis, and Vascular Biology
- Vol. 22 (7), 1194-1199
- https://doi.org/10.1161/01.atv.0000022694.16328.cc
Abstract
Objective— A number of studies have shown that statins decrease morbidity and mortality in patients with cardiovascular diseases. The anti-inflammatory effects of statins have recently been implica...Keywords
This publication has 16 references indexed in Scilit:
- Measurement of C-Reactive Protein for the Targeting of Statin Therapy in the Primary Prevention of Acute Coronary EventsNew England Journal of Medicine, 2001
- Anti-inflammatory effects of simvastatin in subjects with hypercholesterolemiaInternational Journal of Cardiology, 2001
- Levels of sICAM-1, sVCAM-1 and MCP-1 in patients with hyperlipoproteinemia IIa and -IIbInt. Journal of Clinical Pharmacology and Therapeutics, 2001
- Molecular link between cholesterol, cytokines and atherosclerosisMolecular and Cellular Biochemistry, 2001
- Atherosclerosis — An Inflammatory DiseaseNew England Journal of Medicine, 1999
- Primary Prevention of Acute Coronary Events With Lovastatin in Men and Women With Average Cholesterol LevelsJAMA, 1998
- The role of chemokines in inflammationInternational Journal of Clinical and Laboratory Research, 1996
- Ibuprofen inhibits pyrogen-dependent expression of VCAM-1 and ICAM-1 on human endothelial cellsLife Sciences, 1996
- Interleukin 8 Is Induced by Cholesterol Loading of Macrophages and Expressed by Macrophage Foam Cells in Human AtheromaPublished by Elsevier ,1996
- Monocyte chemoattractant protein-1 in human atheromatous plaques.Journal of Clinical Investigation, 1991