Properties of Silver Sulfadiazine-Resistant Enterobacter cloacae
- 1 February 1974
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 5 (2), 199-201
- https://doi.org/10.1128/aac.5.2.199
Abstract
Two silver sulfadiazine-resistant isolates of Enterobacter cloacae obtained in a burns unit where the drug was in use were studied. These strains were resistant to elevated levels of the drug, and they were cross-resistant to silver benzoate, but not to silver nitrate. Growth of the strains in nutritionally poor defined media sensitized them to the inhibitory action of the drug. Exposure of the bacteria to penicillins rendered them susceptible to silver sulfadiazine. The resistant bacteria harbored episomes for resistance to carbenicillin and kanamycin; however, resistance to silver sulfadiazine could not be transferred by these episomes. Twenty-three strains of E. cloacae isolated in a general hospital were sensitive to much lower levels of the drug (≤50 μg/ml).Keywords
This publication has 15 references indexed in Scilit:
- ANTIFUNGAL ACTIVITY OF SILVER SULPHADIAZINEThe Lancet, 1973
- Silver Sulfadiazine: Effect on the Ultrastructure of Pseudomonas aeruginosaAntimicrobial Agents and Chemotherapy, 1973
- Topical chemoprophylaxis for burns: Trials of creams containing silver sulphadiazine and trimethoprimInjury, 1972
- Silver Sulfadiazine: Interaction with Isolated Deoxyribonucleic AcidAntimicrobial Agents and Chemotherapy, 1972
- Silver Sulfadiazine: Effect on the Growth and Metabolism of BacteriaAntimicrobial Agents and Chemotherapy, 1972
- Burns and the Use of Silver Sulphadiazine1Anz Journal of Surgery, 1972
- Opportunistic Infection: A ReviewThe American Journal of the Medical Sciences, 1969
- Gram-negative bacilli in burnsJournal of Clinical Pathology, 1969
- CLINICAL EXPERIENCE WITH SILVER SULFADIAZINE, A NEW TOPICAL AGENT FOR CONTROL OF PSEUDOMONAS INFECTIONS IN BURNSPublished by Wolters Kluwer Health ,1969
- R Factors Mediate Resistance to Mercury, Nickel, and CobaltScience, 1967