Age-dependent distribution of isoamylases in human parotid saliva
- 1 July 1976
- journal article
- Published by Wiley in Clinical Otolaryngology
- Vol. 1 (3), 249-256
- https://doi.org/10.1111/j.1365-2273.1976.tb00884.x
Abstract
The number of isoamylases present in parotid saliva from 53 healthy men and women of different ages was determined. A basic pattern of 6 isoamylases was evident in all samples. With increasing age, an increasing number of additional isoenzymes was observed which migrated faster towards the anode. These 'fast isoamylases' are derived from the basic isoenzymes by deamidation. The significance of deamidation of proteins as age increases as well as the increasing number of 'fast isoamylases' in saliva from mucoviscidosis patients are discussed.Keywords
This publication has 6 references indexed in Scilit:
- Author Index Vol. 36, 1974Stereotactic and Functional Neurosurgery, 1974
- Apparatur zur thermokonstanten Elektrophorese oder Fokussierung und ihre ZusatzteileAnalytical and Bioanalytical Chemistry, 1972
- Structural differences between the isoenzymes of human parotid α-amylaseBiochemistry, 1971
- Controlled Deamidation of Peptides and Proteins: An Experimental Hazard and a Possible Biological TimerProceedings of the National Academy of Sciences, 1970
- THE MAINTENANCE OF THE ACCURACY OF PROTEIN SYNTHESIS AND ITS RELEVANCE TO AGEINGProceedings of the National Academy of Sciences, 1963
- Determination ok amylase activity in biological fluidsClinica Chimica Acta; International Journal of Clinical Chemistry, 1956