COMMON ANTIGENIC DETERMINANTS ON STRUCTURAL PROTEINS P10-12 OF PMFV AND MPMV TYPE-D RETROVIRUSES

Abstract

PMFV [PMF virus], a type D retrovirus isolated from a malignant human embryo cell line, was compared with Mason-Pfizer monkey virus (MPMV) in a sensitive tannic acid enhanced indirect immunodiffusion test. In addition to the previously shown common antigens, both viruses contain identical group-specific antigenic determinants on their p 10-12 as demonstrated with a specific p 10-12 MPMV test system. Interspecies mammalian type C virus antigens were not detected in highly concentrated PMFV preparations.