In a series of cases studied at the U. S. Army General Hospital No. 41, Fox Hills, Staten Island, N. Y., over a period of five months, such interesting manifestations were noted from an endocrinologic and myopathic standpoint, that their publication seems warranted. REPORT OF CASES Case 1. —An advanced instance of polyglandular disturbance, characterized by a dystrophia adiposo-genitalis, precipitated by influenza, associated with a muscular dystrophy, and unusual reactions of the vegetative nervous system. A consideration of the endocrine balance and the metabolism findings is of unusual interest. C. G., white, aged 27 years, was a motorman and rancher by prewar occupation. Habits: Alcoholic beverages indulged in moderately. Used tobacco. He smoked about a dozen cigarettes daily; a pipe occasionally. Family History. —Father living and well; mother dead of unknown cause; no brothers or sisters. No history of tuberculosis; no nervous, mental or endocrinologic diseases in the family. Previous