Detection by electron microscope of rod-shaped organisms in synovial membrane from a patient with the arthritis of Whipple's disease.
Open Access
- 1 December 1976
- journal article
- case report
- Published by BMJ in Annals Of The Rheumatic Diseases
- Vol. 35 (6), 502-509
- https://doi.org/10.1136/ard.35.6.502
Abstract
Rod-shaped organisms identical to those present in the jejunal mucosa have been found in the synovial membrane of a patient with Whipple's disease. These probably caused inflammatory changes which sere reflected in an increase of the cellular content and high enzyme levels (acid phosphatase and 5-nucleotidase) of the synovial fluid. Tetracycline was effective in controlling the bowel lesion but only had a temporary effect upon the arthritis. Erythromycin controlled both the bowel lesion and the arthritis.This publication has 18 references indexed in Scilit:
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