A STUDY OF VACCINAL IMMUNITY IN TISSUE CULTURES
Open Access
- 1 November 1929
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 50 (5), 673-685
- https://doi.org/10.1084/jem.50.5.673
Abstract
Normal corneas inoculated in vitro with vaccine virus and then cultivated in antivaccinal plasma developed typical vaccinal lesions associated with Guarnieri bodies. In such cultures, after an incubation period of 24 or 48 hours, active vaccine virus was demonstrated by means of appropriate methods. Immune corneas inoculated in vitro with vaccine virus and then cultivated in normal or in antivaccinal plasma revealed either very mild vaccinal lesions or none at all. In some of the cultures after 24 and 48 hours of incubation, active vaccine virus was demonstrated.This publication has 10 references indexed in Scilit:
- DEVELOPMENT IN TISSUE CULTURES OF THE INTRACELLULAR CHANGES CHARACTERISTIC OF VACCINAL AND HERPETIC INFECTIONSThe Journal of Experimental Medicine, 1929
- Anti‐vaccinial serum. 1. Protection against generalisation in the rabbit. 2. The time factor‐ in protection experimentsThe Journal of Pathology and Bacteriology, 1929
- Studies on filterable viruses III Further observations on vaccine virus1929
- Isolation by Cataphoresis of Virus from Vaccinia-Recovered RabbitsScience, 1929
- Generalised vaccinia in rabbits with especial reference to lesions in the internal organsThe Journal of Pathology and Bacteriology, 1929
- The action of immune serum on vaccinia and virus III in vitroThe Journal of Pathology and Bacteriology, 1928
- A FILTERABLE VIRUS PRESENT IN THE SUBMAXILLARY GLANDS OF GUINEA PIGSThe Journal of Experimental Medicine, 1926
- GROWTH AND PERSISTENCE OF FILTERABLE VIRUSES IN A TRANSPLANTABLE RABBIT NEOPLASMThe Journal of Experimental Medicine, 1925
- THE PRODUCTION OF ANTIBODIES BY TISSUES LIVING OUTSIDE OF THE ORGANISMThe Journal of Experimental Medicine, 1912
- A STUDY OF CANCER IMMUNITY BY THE METHOD OF CULTIVATING TISSUES OUTSIDE THE BODYThe Journal of Experimental Medicine, 1911