ACTION OF FORMALDEHYDE ON MICROORGANISMS II

Abstract

Neely, W. Brock (The Dow Chemical Co., Midland, Mich.). Action of formaldehyde on microorganisms. II. Formation of 1,3-thiazane-4-carboxylic acid in Aerobacter aerogenes treated with formaldehyde. J. Bacteriol. 85: 1420–1422. 1963.—A culture of Aerobacter aerogenes was found to incorporate C ¹⁴ -labeled formaldehyde into 1,3-thiazane-4-carboxylic acid. The reaction was found to proceed nonenzymatically from homocysteine and formaldehyde. As a consequence of this reaction, the ability of homocysteine to counteract the effects of formaldehyde on A. aerogenes was investigated.