IN VITRO AND IN VIVO LABORATORY EVALUATION OF CEPHALOTHIN, A NEW BROAD SPECTRUM ANTIBIOTIC
- 1 December 1962
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 84 (6), 1292-+
- https://doi.org/10.1128/jb.84.6.1292-1296.1962
Abstract
Cephalothin, a new cephalosporin antibiotic, is the sodium salt of 7-(thiophene-2-acetamido) cephalosporanic acid. The activity of this antibiotic against a variety of gram-positive and gram-negative bacteria is described as determined by the tube-dilution and disc-plate methods. Correlations of the results of the therapy of experimental infections in mice with in vitro sensitivity to cephalothin are presented.Keywords
This publication has 5 references indexed in Scilit:
- Chemistry of Cephalosporin Antibiotics. II. Preparation of a New Class of Antibiotics and the Relation of Structure to ActivityJournal of the American Chemical Society, 1962
- Antigenic Hemophilus Pertussis Vaccines Grown on Charcoal AgarThe Journal of Infectious Diseases, 1953
- Pertussis Vaccine Prepared with Phase-I Cultures Grown in Fluid Medium.1946
- Pertussis Vaccine Prepared with Phase-I Cultures Grown in Fluid MediumAmerican Journal of Public Health and the Nations Health, 1946
- A SIMPLE METHOD OF ESTIMATING FIFTY PER CENT ENDPOINTS12American Journal of Epidemiology, 1938