Experimental Aminonucleoside Nephrosis.(I): Action of Cortisone on Aldosterone and Corticosterone Production
- 1 June 1958
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 98 (2), 334-339
- https://doi.org/10.3181/00379727-98-24035
Abstract
An increased rate of aldosterone production after induction of aminonucleoside nephrosis in rats was confirmed. After short-term treatment with cortisone acetate, in dosage of 350 and 500 [mu]/day, corticosterone production of both normal and nephrotic animals was decreased to 1/3 of their respective controls. Cortisone reverted increased aldosterone secretion of nephrotic rats to normal; this was accompanied by marked loss or even total disappearance of ascites.Keywords
This publication has 6 references indexed in Scilit:
- ALDOSTERONE IN THE ADRENAL VEIN BLOOD OF NEPHROTIC RATSEndocrinology, 1957
- THE EFFECT OF CORTICOSTEROID INJECTION ON ALDOSTERONE SECRETION1Endocrinology, 1956
- Experimental Nephrotic Syndrome Induced in Rats by Aminonucleoside. Renal Lesions and Body Electrolyte Composition.Experimental Biology and Medicine, 1955
- IN VITRO BIOASSAY OF CORTICOTROPIN: MODIFICATION AND STATISTICAL TREATMENTEndocrinology, 1955
- A QUANTITATIVE METHOD FOR THE BIOASSAY OF THE EFFECT OF ADRENAL CORTICAL STEROIDS ON MINERAL METABOLISMEndocrinology, 1952
- Methods of paper chromatography of steroids applicable to the study of steroids in mammalian blood and tissuesBiochemical Journal, 1952