Hu-1: Major Histocompatibility Locus in Man
- 16 June 1967
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 156 (3781), 1506-1508
- https://doi.org/10.1126/science.156.3781.1506
Abstract
A single locus with 15 or more alleles controls reactivity in mixed leukocyte culture tests. Genes at this locus also control most of the specificities measured by cytotoxic antiserums to leukocytes. Both of these tests can be used to predict survival of skin grafts. It is proposed that this is the major histocompatibility locus in man.This publication has 8 references indexed in Scilit:
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- PREDICTIVE VALUE OF RESULTS OF MIXED LEUKOCYTE CULTURES FOR SKIN ALLOGRAFT SURVIVAL IN MANTransplantation, 1967
- Leukocyte Antigens and the Mixed Lymphocyte Culture ReactionVox Sanguinis, 1967
- Mixed Leukocyte Reactions and Histocompatibility in RatsScience, 1967
- THE CUMULATIVE EFFECT OF HISTOCOMPATIBILITY ANTIGENS1Transplantation, 1966
- One-Way Stimulation in Mixed Leukocyte CulturesScience, 1966
- THE NUMBER OF ALLELES THAT CAN BE MAINTAINED IN A FINITE POPULATIONGenetics, 1964