Type I interferons are essential mediators of apoptotic death in virally infected cells
Open Access
- 1 January 1998
- journal article
- research article
- Published by Wiley in Genes to Cells
- Vol. 3 (1), 29-37
- https://doi.org/10.1046/j.1365-2443.1998.00164.x
Abstract
Background The interferons (IFNs) have been extensively studied in the context of host defence against viral infection. In the established model of IFN action, virally infected cells secrete type I ...Keywords
This publication has 38 references indexed in Scilit:
- Activation of the STAT Signaling Pathway Can Cause Expression of Caspase 1 and ApoptosisMolecular and Cellular Biology, 1997
- A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosisProceedings of the National Academy of Sciences, 1997
- Virus-Induced ApoptosisPublished by Elsevier ,1997
- Host factors and the pathogenesis of HIV-induced diseaseNature, 1996
- ISGF3γ p48, a specificity switch for interferon activated transcription factorsCytokine & Growth Factor Reviews, 1996
- Targeted Disruption of the Mouse Stat1 Gene Results in Compromised Innate Immunity to Viral DiseaseCell, 1996
- Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling ProteinsScience, 1994
- Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death.Proceedings of the National Academy of Sciences, 1993
- Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.The Journal of cell biology, 1992
- Induction of bcl-2 expression by epstein-barr virus latent membrane protein 1 protects infected B cells from programmed cell deathCell, 1991