Regional mapping of the HLA on the short arm of chromosome 6
- 1 March 1979
- journal article
- research article
- Published by Wiley in Clinical Genetics
- Vol. 15 (3), 245-251
- https://doi.org/10.1111/j.1399-0004.1979.tb00975.x
Abstract
A detailed gene marker study was performed on a partial 6p trisomic child resulting from a balanced maternal translocation t (2;6) (p 2505; p 2105). HLA typing and mixed lymphocyte reaction showed that the breakpoint on chromosome 6 was located within the HLA gene cluster, allowing an accurate location of the D determinants. Localization of the P blood group locus within the region 6 p 2105 to 6 p ter was excluded.Keywords
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