THE RESPONSE OF THE HUMAN FETAL REPRODUCTIVE SYSTEM TO THE ADMINISTRATION OF DIETHYLSTILBESTROL AND TESTOSTERONE PROPIONATE DURING EARLY PREGNANCY1

Abstract

The admn. of large amts. of diethylstilbestrol or testosterone propionate to mothers early in pregnancy and for the length of time given in this study did not produce any demonstrable changes in the appearance of the gonads or genital organs of 6 [male] fetuses. These drugs administered in therapeutic doses early in pregnancy will not affect adversely the development of the genital organs of the human [male] fetus. The material is inadequate for conclusions concerning the [female] fetus although the one fetus examined was normal.