CORTICOTROPIC ACTIVITY OF HUMAN BLOOD*
- 1 June 1954
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 14 (6), 597-607
- https://doi.org/10.1210/jcem-14-6-597
Abstract
The various procedures employed in the assay for corticotropin in human blood were described and analyzed. Only 2 of these procedures[long dash]the application of the assay method of Sayers and associates to untreated serum or plasma and to extracts prepared by the oxycellulose process[long dash]have yielded to the present time results which seem to be compatible with one another. The results obtained with these 2 procedures indicate that corticotropin is measurably present in the blood of patients with untreated Addison''s disease, adrenogenital syndrome, and a few miscellaneous disorders. Corticotropin is not demonstrable in the blood of patients with Cushing''s disease, nor in the blood of normal persons.Keywords
This publication has 9 references indexed in Scilit:
- PRELIMINARY STUDIES ON BLOOD ACTH IN MAN*Journal of Clinical Endocrinology & Metabolism, 1953
- Blood Adrenocorticotrophin in Children with Congenital Adrenal Hyperplasia.Experimental Biology and Medicine, 1953
- A Technic for Determination of Adrenocorticotrophin in Blood.Experimental Biology and Medicine, 1952
- INACTIVATION OF ADRENOCORTICOTROPIC HORMONE IN VITRO BY TISSUES*Endocrinology, 1952
- Fate and Excretion of Adrenocorticotrophic Hormone.Experimental Biology and Medicine, 1951
- EXTRACTION AND PURIFICATION OF CORTICOTROPINJournal of Biological Chemistry, 1950
- ADRENOTROPHIC ACTIVITY OF HUMAN BLOOD1Endocrinology, 1949
- REGULATION OF PITUITARY ADRENOCORTICOTROPHIC ACTIVITY DURING THE RESPONSE OF THE RAT TO ACUTE STRESS1Endocrinology, 1947
- BIOASSAY OF ADRENOCORTICOTROPIC HORMONE1Endocrinology, 1943