PRIMARY IMMUNE RESPONSE IN GRAFTED CELLS
Open Access
- 1 June 1967
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 125 (6), 967-981
- https://doi.org/10.1084/jem.125.6.967
Abstract
The primary immune response elicited by host antigens in a grafted population of immunologically competent cells has been compared in conditions where the same dose of parental cells were grafted simultaneously to F1 hybrid embryos of 13 or 17 days of age. The enlarged chimeric spleens harvested 4 days later were analyzed for donor cell proliferation by using the sex chromosomes as karyological markers, and for proliferation of immunological activity by means of transfer to secondary hosts of the same genotype.This publication has 11 references indexed in Scilit:
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