Lack of H5N1 Avian Influenza Transmission to Hospital Employees, Hanoi, 2004
Open Access
- 1 February 2005
- journal article
- Published by Centers for Disease Control and Prevention (CDC) in Emerging Infectious Diseases
- Vol. 11 (2), 210-215
- https://doi.org/10.3201/eid1102.041075
Abstract
To establish whether human-to-human transmission of influenza A H5N1 occurred in the healthcare setting in Vietnam, we conducted a cross-sectional seroprevalence survey among hospital employees exposed to 4 confirmed and 1 probable H5N1 case-patients or their clinical specimens. Eighty-three (95.4%) of 87 eligible employees completed a questionnaire and provided a serum sample, which was tested for antibodies to influenza A H5N1. Ninety-five percent reported exposure to >1 H5N1 case-patients; 59 (72.0%) reported symptoms, and 2 (2.4%) fulfilled the definition for a possible H5N1 secondary case-patient. No study participants had detectable antibodies to influenza A H5N1. The data suggest that the H5N1 viruses responsible for human cases in Vietnam in January 2004 are not readily transmitted from person to person. However, influenza viruses are genetically variable, and transmissibility is difficult to predict. Therefore, persons providing care for H5N1 patients should continue to take measures to protect themselves.Keywords
This publication has 8 references indexed in Scilit:
- Avian Influenza A (H5N1) in 10 Patients in VietnamNew England Journal of Medicine, 2004
- Risk of Influenza A (H5N1) Infection among Poultry Workers, Hong Kong, 1997–1998The Journal of Infectious Diseases, 2002
- Risk of Influenza A (H5N1) Infection among Health Care Workers Exposed to Patients with Influenza A (H5N1), Hong KongThe Journal of Infectious Diseases, 2000
- Antibody Response in Individuals Infected with Avian Influenza A (H5N1) Viruses and Detection of Anti‐H5 Antibody among Household and Social ContactsThe Journal of Infectious Diseases, 1999
- Detection of Antibody to Avian Influenza A (H5N1) Virus in Human Serum by Using a Combination of Serologic AssaysJournal of Clinical Microbiology, 1999
- Clinical features and rapid viral diagnosis of human disease associated with avian influenza A H5N1 virusThe Lancet, 1998
- Influenza virus: transmission between species and relevance to emergence of the next human pandemicPublished by Springer Nature ,1997