Influence of Amino-Acids on Adrenal Enlargement, Nephrosclerosis and Hypertension by Anterior Pituitary Preparations.
- 1 December 1948
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 69 (3), 591-593
- https://doi.org/10.3181/00379727-69-16797
Abstract
Adrenal enlargement, nephrosclerosis and hypertension were produced by a lyophilized anterior pituitary (LAP) prepn. in rats kept on a synthetic diet containing no protein, but an adequate amt. of amino-acids. The severity of the lesions was less marked, however, than in rats receiving an equivalent amt. of N in the form of a casein-hydrolysate. It appears that amino-acids suffice to sensitize the organism to the production of hypertensive disease by LAP. This is noteworthy since no such pathologic changes can be produced by LAP on other diets deficient in proteins.Keywords
This publication has 2 references indexed in Scilit:
- THE DIET AND HORMONALLY INDUCED NEPHROSCLEROSISCanadian Journal of Research, 1948
- THE GENERAL ADAPTATION SYNDROME AND THE DISEASES OF ADAPTATION1Journal of Clinical Endocrinology & Metabolism, 1946