The Biochemistry of Somatic Hypermutation
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- 1 April 2008
- journal article
- review article
- Published by Annual Reviews in Annual Review of Immunology
- Vol. 26 (1), 481-511
- https://doi.org/10.1146/annurev.immunol.26.021607.090236
Abstract
Affinity maturation of the humoral response is mediated by somatic hypermutation of the immunoglobulin (Ig) genes and selection of higher-affinity B cell clones. Activation-induced cytidine deamina...Keywords
This publication has 170 references indexed in Scilit:
- Class Switch Recombination and Somatic Hypermutation in Early Mouse B Cells Are Mediated by B Cell and Toll-like ReceptorsImmunity, 2007
- A unified view of base excision repair: Lesion-dependent protein complexes regulated by post-translational modificationDNA Repair, 2007
- Down-regulation of DNA polymerase β accompanies somatic hypermutation in human BL2 cell linesDNA Repair, 2006
- Involvement of Rad18 in somatic hypermutationProceedings of the National Academy of Sciences, 2006
- RAD18‐independent ubiquitination of proliferating‐cell nuclear antigen in the avian cell line DT40EMBO Reports, 2006
- Regulation of hypermutation by activation-induced cytidine deaminase phosphorylationProceedings of the National Academy of Sciences, 2006
- APOBEC3G DNA deaminase acts processively 3′ → 5′ on single-stranded DNANature Structural & Molecular Biology, 2006
- The multifaceted mismatch-repair systemNature Reviews Molecular Cell Biology, 2006
- AID binds to transcription-induced structures in c-MYC that map to regions associated with translocation and hypermutationOncogene, 2005
- Uracil in DNA – occurrence, consequences and repairOncogene, 2002