THE EFFECT OF ASCORBIC ACID ON HEMORRHAGIC SHOCK IN THE GUINEA PIG

Abstract

It has been possible to prevent the development of hemorrhagic shock in the guinea pig by pretreatment with 200 mg. of ascorbic acid. All but one (94%) of the primed animals survived while all but 2 (90%) of the controls died of hemorrhagic shock. The course followed by the hemorrhage, as to magnitude of bleeding vol. and duration of hypotension, was identical in both groups.