The Annexins and Exocytosis
- 6 November 1992
- journal article
- review article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 258 (5084), 924-931
- https://doi.org/10.1126/science.1439804
Abstract
The annexins are a group of homologous proteins that bind phospholipids in the presence of calcium. They may provide a major pathway for communication between cellular membranes and their cytoplasmic environment. Annexins have a characteristic "bivalent" activity in the sense that they can draw two membranes together when activated by calcium. This has led to the hypothesis that certain members of this protein family may initiate contact and fusion between a secretory vesicle membrane and the plasma membrane during the process of exocytosis.Keywords
This publication has 108 references indexed in Scilit:
- Highly sequential binding of protein kinase C and related proteins to membranesBiochemistry, 1991
- Crystallization and preliminary X-ray studies of human vascular anticoagulant proteinJournal of Molecular Biology, 1989
- Crystallization of p68 on lipid monolayers and as three-dimensional single crystalsJournal of Molecular Biology, 1989
- The annexin family of calcium-binding proteins: Review articleCell Calcium, 1989
- In vitro protein kinase C phosphorylation sites of placental lipocortinBiochemistry, 1988
- Antibodies to calcium/phospholipid binding protein (calelectrin) recognize neurons, astrocytes and schwann cells in the nervous system of ratNeuroscience Letters, 1988
- Calcium dependence of the binding of synexin to isolated chromaffin granulesBiochemical and Biophysical Research Communications, 1983
- Catecholamine Secretion by Chemically Skinned Cultured Chromaffm CellsJournal of Neurochemistry, 1983
- Calcium-dependence of catecholamine release from bovine adrenal medullary cells after exposure to intense electric fieldsThe Journal of Membrane Biology, 1982
- Secretory vesicle — Cytosol interactions in exocytosis: Isolation by Ca2+-dependent affinity chromatography of proteins that bind to the chromaffin granule membraneBiochemical and Biophysical Research Communications, 1981